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The Hu Lab

The Hu Lab for Brain Tumor Evolution and Therapy

Exploring the Genetic and Epigenetic Events Affecting Brain Tumor Development and Resistance to Therapy

The laboratory of Baoli Hu, PhD, investigates the genetic and epigenetic events that contribute to the evolution of brain tumors. The long-term goals of the lab are to achieve a better understanding of brain tumor biology and to develop more effective diagnoses and therapeutic strategies for the treatment of brain cancer.

Cancer is increasingly being viewed as an ecosystem where the cancer cells dynamically evolve and spatiotemporally communicate with the surrounding cellular environment. Deciphering this evolutionary complexity allows us to better understand brain tumor initiation, progression, recurrence, and drug resistance. The Hu Lab for Brain Tumor Evolution and Therapy is focused on glioma and medulloblastoma, the most common malignant brain tumors in adults and children, respectively.