Ten to 50 percent of pediatric cancer and tumors occur as the result of an inherited gene change. Children with a hereditary cancer predisposition syndrome are at increased risk of getting cancer or tumors throughout their lifetime.
Our clinic helps families learn the role of genetics in causing cancer so we can screen for and monitor it in childhood.
Certain types of tumors or cancers are more likely linked to genetics and may call for an exam in the clinic.
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Sometimes other factors increase the risk of a hereditary cancer predisposition syndrome, such as:
- Having more than one form of cancer under the age of 20.
- A strong family history of cancers.
- An adult form of cancer occurring at a younger age than normal.
We suggest making an appointment at the Pediatric Cancer Predisposition Program in these cases:
- History of a rare childhood cancer or brain tumor with a strong hereditary link.
- History of pediatric cancer plus a family history of cancer.
- Multifocal/bilateral cancer, or multiple primary tumors.
- Early-onset tumor not normally seen in kids (adult-type cancer in a child).
- Strong family history of cancer or related types of cancer in a number of close relatives.
- A child with cancer and a history of developmental delay, autism, birth defects, or dysmorphic features.
- A child with a known family history of a cancer predisposition syndrome or a cancer gene mutation.
We also provide ongoing care for children with diagnosed inherited cancer syndromes.
