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For more information about research, please call our main office at 412-692-6438.
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The physicians at UPMC Children’s Hospital of Pittsburgh's Blood and Marrow Transplantation and Cellular Therapies (BMTCT) program continuously strive to improve cellular therapies for treatment of childhood cancer and blood diseases.
The division’s research is pursuing new treatment methods, such as reduced-intensity conditioning, that will make marrow and cord blood transplants kinder, gentler, and safer for pediatric patients. The team’s ultimate goals are to reduce the complication rate and improve the quality of life for children undergoing these specialized procedures.
In pursuit of these goals, investigators are active on multiple fronts, using both basic laboratory research and clinical trials. In the laboratory, scientists are studying immune reconstitution, tolerance and alloreacivity, and cellular immunotherapy. Clinical investigations are underway to trial novel therapies for treating Crohn’s disease and other autoimmune diseases, Krabbe disease and other leukodystrophies, MPS syndromes, and high-risk leukemias.
Other BMTCT studies are focused on understanding the relationship between individual genetic variability and post-transplant outcomes, including graft-versus-host disease (GVHD). Our investigators have learned that individual variation in immune-response genes influences a child’s outcome after transplantation. This has led to further clinical research focused on therapies that move away from the "one size fits all" approach to tailored treatments that are based on a each patient’s specific metabolic needs.
The Pitt+Me Registry connects community members and patients of all ages with researchers at the University of Pittsburgh and UPMC. Parents who enroll their children in the Pitt+Me Registry will learn about research studies in areas of their choosing related to their child’s health.
Children's Hospital's main campus is located in the Lawrenceville neighborhood. Our main hospital address is:
UPMC Children’s Hospital of Pittsburgh One Children’s Hospital Way 4401 Penn Ave. Pittsburgh, PA 15224
In addition to the main hospital, Children's has many convenient locations in other neighborhoods throughout the greater Pittsburgh region.
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To pay your bill online, please visit UPMC's online bill payment system.
Interested in giving to Children's Hospital? Support the hospital by making a donation online, joining our Heroes in Healing monthly donor program, or visiting our site to learn about the other ways you can give back.