What Is Muromonab-CD3?
Muromonab-CD3 is also referred to as OKT3.
Uses
Muromonab-CD3 (Orthoclone OKT3®) is an immunosuppressant drug used to reduce the natural immunity of patients who receive organ transplants such as liver transplants.
What Does Muromonab-CD3 Do?
Muromonab-CD3 is a monoclonal antibody that prevents white blood cells from causing organ rejection.
Muromonab-CD3 Dosage
Muromonab-CD3 or OKT3 is a liquid that is given by injection.
Muromonab-CD3 Side Effects
Common side effects of muromonab-CD3 include:
- Increased risk of infection. You can help to prevent infection by making sure your child avoids contact with people who are ill.
- Reduction in the number of blood cells needed for clotting. To prevent bleeding, avoid situations where bruising or injury might occur.
- Chest pain, dizziness, fever and chills, shortness of breath, stomach upset, and trembling or shaking of the hands within a few hours after taking the first dose. These effects should lessen substantially after the second dose and should not occur after that.
Other common side effects of muromonab-CD3 include:
- Diarrhea
- Faintness
- Headache
- Nausea
- Vomiting
- Rapid heartbeat
Rare side effects of muromonab-CD3 include:
- Stiff neck
- Light sensitivity
- Confusion
- Hallucinations
- Unusual tiredness
If any of these side effects continues or becomes bothersome, inform your child's doctor.
Muromonab-CD3 Drug Interactions
Tell your transplant doctor or pharmacist about any prescription or over-the-counter medication that you are taking, so you can be warned of interactions and prevent them.
